The HMGB1/RAGE axis triggers neutrophil-mediated injury amplification following necrosis

In contrast to microbially triggered inflammation, mechanisms promoting sterile inflammation remain poorly understood. Damage-associated molecular patterns (DAMPs) are considered key inducers of sterile inflammation following cell death, but the relative contribution of specific DAMPs, including hig...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Huebener, Peter, Pradere, Jean-Philippe, Hernandez, Celine, Gwak, Geum-Youn, Caviglia, Jorge Matias, Mu, Xueru, Loike, John D., Jenkins, Rosalind E., Antoine, Daniel J., Schwabe, Robert F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319429/
https://ncbi.nlm.nih.gov/pubmed/25562324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76887
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