Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis

Nonalcoholic fatty liver disease (NAFLD) encompasses a range of manifestations, including steatosis and cirrhosis. Progressive disease is characterized by hepatic leukocyte accumulation in the form of steatohepatitis. The adhesion molecule vascular adhesion protein-1 (VAP-1) is a membrane-bound amin...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Weston, Chris J., Shepherd, Emma L., Claridge, Lee C., Rantakari, Pia, Curbishley, Stuart M., Tomlinson, Jeremy W., Hubscher, Stefan G., Reynolds, Gary M., Aalto, Kristiina, Anstee, Quentin M., Jalkanen, Sirpa, Salmi, Marko, Smith, David J., Day, Christopher P., Adams, David H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 2014
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319424/
https://ncbi.nlm.nih.gov/pubmed/25562318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI73722
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