Chargement en cours...
Fighting polyglutamine disease by wrestling with SUMO
Spinobulbar muscular atrophy (SBMA) is an X-linked disease characterized by degeneration of motor neurons, muscle atrophy, and progressive weakness. It is caused by a polyglutamine (polyQ) expansion in the androgen receptor (AR), a transcription factor that is activated upon hormone binding. The pol...
Enregistré dans:
| Publié dans: | J Clin Invest |
|---|---|
| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2015
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4319405/ https://ncbi.nlm.nih.gov/pubmed/25607836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80278 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|