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Elongation factor Tu resistant to kirromycin in an Esherichia coli mutant altered in both tuf genes

A mutant of Escherichia coli is described that displays kirromycin resistance in a cell-free system by virtue of an altered elongation factor Tu (EF-Tu). In poly(U)-directed poly(Phe) synthesis the kirromycin resistance of the crystallized enzyme ranged between a factor of 80 and 700, depending on t...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Fischer, Eckhard, Wolf, Heinz, Hantke, Klaus, Parmeggiani, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1977
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Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431937/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/337296/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.10.4341
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