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Engulfment of Activated Apoptotic Cells Abolishes TGF-β–Mediated Immunoregulation via the Induction of IL-6

Phagocytosis of apoptotic cells (ACs) is usually a potent immunoregulatory signal but can also promote inflammation. In this article, we show that administration of apoptotic dendritic cells (DCs) inhibited inflammation in vivo through increasing production of TGF-β from intrinsic DCs and B cells. H...

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Опубликовано в: :J Immunol
Главные авторы: Notley, Clare A., Brown, Mark A., McGovern, Jenny L., Jordan, Christine K., Ehrenstein, Michael R.
Формат: Artigo
Язык:Inglês
Опубликовано: AAI 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319310/
https://ncbi.nlm.nih.gov/pubmed/25601923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401256
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