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Transplanted Bone Marrow–Derived Circulating PDGFRα(+) Cells Restore Type VII Collagen in Recessive Dystrophic Epidermolysis Bullosa Mouse Skin Graft

Recessive dystrophic epidermolysis bullosa (RDEB) is an intractable genetic blistering skin disease in which the epithelial structure easily separates from the underlying dermis because of genetic loss of functional type VII collagen (Col7) in the cutaneous basement membrane zone. Recent studies hav...

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Vydáno v:J Immunol
Hlavní autoři: Iinuma, Shin, Aikawa, Eriko, Tamai, Katsuto, Fujita, Ryo, Kikuchi, Yasushi, Chino, Takenao, Kikuta, Junichi, McGrath, John A., Uitto, Jouni, Ishii, Masaru, Iizuka, Hajime, Kaneda, Yasufumi
Médium: Artigo
Jazyk:Inglês
Vydáno: AAI 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319308/
https://ncbi.nlm.nih.gov/pubmed/25601922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400914
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