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K(+) Congeners That Do Not Compromise Na(+) Activation of the Na(+),K(+)-ATPase: HYDRATION OF THE ION BINDING CAVITY LIKELY CONTROLS ION SELECTIVITY
The Na(+),K(+)-ATPase is essential for ionic homeostasis in animal cells. The dephosphoenzyme contains Na(+) selective inward facing sites, whereas the phosphoenzyme contains K(+) selective outward facing sites. Under normal physiological conditions, K(+) inhibits cytoplasmic Na(+) activation of the...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4319036/ https://ncbi.nlm.nih.gov/pubmed/25533461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.577486 |
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