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Structural Basis for Replication Origin Unwinding by an Initiator Primase of Plasmid ColE2-P9: DUPLEX DNA UNWINDING BY A SINGLE PROTEIN
Duplex DNA is generally unwound by protein oligomers prior to replication. The Rep protein of plasmid ColE2-P9 (34 kDa) is an essential initiator for plasmid DNA replication. This protein binds the replication origin (Ori) in a sequence-specific manner as a monomer and unwinds DNA. Here we present t...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4319026/ https://ncbi.nlm.nih.gov/pubmed/25538245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.595645 |
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