Adverse Outcome Pathway (AOP) Development I: Strategies and Principles

An adverse outcome pathway (AOP) is a conceptual framework that organizes existing knowledge concerning biologically plausible, and empirically supported, links between molecular-level perturbation of a biological system and an adverse outcome at a level of biological organization of regulatory rele...

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Detalhes bibliográficos
Publicado no:Toxicol Sci
Main Authors: Villeneuve, Daniel L., Crump, Doug, Garcia-Reyero, Natàlia, Hecker, Markus, Hutchinson, Thomas H., LaLone, Carlie A., Landesmann, Brigitte, Lettieri, Teresa, Munn, Sharon, Nepelska, Malgorzata, Ottinger, Mary Ann, Vergauwen, Lucia, Whelan, Maurice
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Forum: Use of Adverse Outcome Pathways in Toxicology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318923/
https://ncbi.nlm.nih.gov/pubmed/25466378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfu199
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