Efficacy of B-Cell Targeted Therapy With Rituximab in Patients With Active Moderate to Severe Graves' Orbitopathy: A Randomized Controlled Study

BACKGROUND: Preliminary studies have shown that rituximab (RTX) is effective in the treatment of active Graves' orbitopathy (GO). METHODS: We conducted a double-blind, randomized trial (European Clinical Trials Database [EudraCT] 2007-003910-33) to compare RTX with iv methylprednisolone (ivMP)...

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Detalhes bibliográficos
Publicado no:J Clin Endocrinol Metab
Main Authors: Salvi, Mario, Vannucchi, Guia, Currò, Nicola, Campi, Irene, Covelli, Danila, Dazzi, Davide, Simonetta, Simona, Guastella, Claudio, Pignataro, Lorenzo, Avignone, Sabrina, Beck-Peccoz, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318899/
https://ncbi.nlm.nih.gov/pubmed/25494967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-3014
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