Histrionicotoxin enhances agonist-induced desensitization of acetylcholine receptor.
Dihydroisohistrionicotoxin inhibits acetylcholine receptor-dependent 22Na+ uptake of cultured chick muscle cells with a KI of 0.2 micrometer. The inhibition is noncompetitive with respect to agonists. The toxin enhances desensitization of the receptor by agonists which is accompanied by a 10-fold in...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1977
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431872/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/272000/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.12.5754 |
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