Histrionicotoxin enhances agonist-induced desensitization of acetylcholine receptor.
Dihydroisohistrionicotoxin inhibits acetylcholine receptor-dependent 22Na+ uptake of cultured chick muscle cells with a KI of 0.2 micrometer. The inhibition is noncompetitive with respect to agonists. The toxin enhances desensitization of the receptor by agonists which is accompanied by a 10-fold in...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
1977
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431872/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/272000/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.12.5754 |
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