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RAS mutations predict radiologic and pathologic response in patients treated with chemotherapy prior to resection of colorectal liver metastases

PURPOSE: RAS mutations have been reported to be a potential prognostic factor in patients with colorectal liver metastases (CLM). However, the impact of RAS mutations on response to chemotherapy remains unclear. We sought to determine the association between RAS mutations and response to preoperativ...

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Bibliographische Detailangaben
Veröffentlicht in:Ann Surg Oncol
Hauptverfasser: Zimmitti, Giuseppe, Shindoh, Junichi, Mise, Yoshihiro, Kopetz, Scott, Loyer, Evelyne M., Andreou, Andreas, Cooper, Amanda B., Kaur, Harmeet, Aloia, Thomas A., Maru, Dipen M., Vauthey, Jean-Nicolas
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318708/
https://ncbi.nlm.nih.gov/pubmed/25227306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1245/s10434-014-4042-6
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