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Diagnostic Screening Workflow for Mutations in the BRCA1 and BRCA2 Genes

OBJECTIVES: Screening for mutations in large genes is challenging in a molecular diagnostic environment. Sanger-based DNA sequencing methods are largely used; however, massively parallel sequencing (MPS) can accommodate increasing test demands and financial constraints. This study aimed to establish...

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Detalhes bibliográficos
Publicado no:Sultan Qaboos Univ Med J
Main Authors: Lai, Stella, Brookes, Clare, Prosser, Debra O., Lan, Chuan-Ching, Doherty, Elaine, Love, Donald R.
Formato: Artigo
Idioma:Inglês
Publicado em: Sultan Qaboos University Medical Journal, College of Medicine & Health Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318608/
https://ncbi.nlm.nih.gov/pubmed/25685387
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