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Injectable, spontaneously assembling inorganic scaffolds modulate immune cells in vivo and increase vaccine efficacy

Materials implanted in the body to program host immune cells are a promising alternative to transplantation of ex vivo–manipulated cells to direct an immune response, but required a surgical procedure. Here we demonstrate that high-aspectratio, mesoporous silica rods (MSRs) injected with a needle sp...

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Detalhes bibliográficos
Publicado no:Nat Biotechnol
Main Authors: Kim, Jaeyun, Li, Weiwei Aileen, Choi, Youngjin, Lewin, Sarah A., Verbeke, Catia S., Dranoff, Glenn, Mooney, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318563/
https://ncbi.nlm.nih.gov/pubmed/25485616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3071
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