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Microsurgically produced homozygous-diploid uniparental mice

Shortly after fertilization, either the male or the female pronucleus was microsurgically removed from 202 F(1) hybrid eggs derived from crosses of two inbred strains. Subsequent incubation of these haploid eggs in medium containing cytochalasin B, which inhibits cytokinesis but not nuclear division...

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Detalhes bibliográficos
Main Authors: Hoppe, Peter C., Illmensee, Karl
Formato: Artigo
Idioma:Inglês
Publicado em: 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC431849/
https://ncbi.nlm.nih.gov/pubmed/271993
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