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Variable and constant parts of the immunoglobulin light chain gene of a mouse myeloma cell are 1250 nontranslated bases apart.

A DNA fragment carrying an immunoglobulin gene coding for both variable (V) and constant (C) regions of a mouse lambda light chain was enriched about 15-fold from a total endonuclease EcoRI digest of a plasmacytoma (HOPC 2020) DNA by preparative agarose gel electrophoresis. The DNA fraction was used...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Brack, C, Tonegawa, S
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1977
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431846/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/414223/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.12.5652
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