Non-stochastic reprogramming from a privileged somatic cell state

Reprogramming somatic cells to induced pluripotency by Yamanaka factors is usually slow and inefficient, and is thought to be a stochastic process. We identified a privileged somatic cell state, from which acquisition of pluripotency could occur in a non-stochastic manner. Subsets of murine hematopo...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Guo, Shangqin, Zi, Xiaoyuan, Schulz, Vincent P., Cheng, Jijun, Zhong, Mei, Koochaki, Sebastian H.J., Megyola, Cynthia M., Pan, Xinghua, Heydari, Kartoosh, Weissman, Sherman M., Gallagher, Patrick G., Krause, Diane S., Fan, Rong, Lu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318260/
https://ncbi.nlm.nih.gov/pubmed/24486105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.01.020
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