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IND-Directed Safety and Biodistribution Study of Intravenously Injected Cetuximab-IRDye800 in Cynomolgus Macaques
PURPOSE: The use of receptor-targeted antibodies conjugated to fluorophores is actively being explored for real-time imaging of disease states, however, the toxicity of the bioconjugate has not been assessed in non-human primates. PROCEDURES: To this end, the in vivo toxicity and pharmacokinetics of...
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| Publicado no: | Mol Imaging Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4318248/ https://ncbi.nlm.nih.gov/pubmed/25080323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-014-0773-9 |
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