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Post-translational cleavage of presecretory proteins with an extract of rough microsomes from dog pancreas containing signal peptidase activity.

The protease(s) responsible for removing the amino-terminal extension of nascent presecretory proteins (signal peptidase) has been extracted from rough microsomes of dog pancreas with the detergent sodium deoxycholate. Preprolactin and pre-growth-hormone, prepared by in vitro translation of bovine p...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Jackson, R C, Blobel, G
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1977
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431824/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/271987/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.12.5598
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