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Aquaporin-1 Promoter Hypermethylation Is Associated with Improved Prognosis in Salivary Gland Adenoid Cystic Carcinoma

OBJECTIVES: Aquaporin-1 (AQP1) is a candidate oncogene that is epigenetically modified in adenoid cystic carcinoma (ACC). We sought to (1) assess AQP1 promoter methylation and expression in an ACC cohort, (2) identify correlations between AQP1 and clinical outcomes, and (3) explore the role of AQP1...

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Detalhes bibliográficos
Publicado no:Otolaryngol Head Neck Surg
Main Authors: Tan, Marietta, Shao, Chunbo, Bishop, Justin A., Feng, Zhaoyong, Trock, Bruce J., Westra, William H., Ha, Patrick K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4318231/
https://ncbi.nlm.nih.gov/pubmed/24493792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0194599814521569
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