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Nerve growth factor prevents vinblastine destructive effects on sympathetic ganglia in newborn mice.

Vinblastine injections in newborn mice produce severe atrophy of sympathetic ganglia; after a 7-day treatment the ganglia are 80% reduced in volume. Histological examinations show that this effect is due to a marked decrease in the neuronal cell population. The most precocious ultra-structural alter...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Chen, M G, Chen, J S, Calissano, P, Levi-Montalcini, R
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1977
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431807/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/271981/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.12.5559
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