Liver-directed gene therapy: quantitative evaluation of promoter elements by using in vivo retroviral transduction.

Liver-directed gene therapy will be applicable to many inherited diseases. Although various protocols have been devised for in vivo delivery of retrovirus, comparison of hepatocyte transduction frequencies has been difficult due to variations in retroviral titer and a paucity of DNA data. We have pr...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Rettinger, S D, Kennedy, S C, Wu, X, Saylors, R L, Hafenrichter, D G, Flye, M W, Ponder, K P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43179/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8108431/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.4.1460
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