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Loss of B-cell translocation gene 2 expression in estrogen receptor-positive breast cancer predicts tamoxifen resistance

B-cell translocation gene 2 (BTG2), a gene suppressed in a subset of aggressive breast cancer, is repressed by estrogen. BTG2 inhibits the expression of HER ligands and promotes AKT activation, which plays an essential role in the tamoxifen resistance of estrogen receptor (ER)-positive breast cancer...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cancer Sci
Asıl Yazarlar: Takahashi, Maiko, Hayashida, Tetsu, Okazaki, Hiroshi, Miyao, Kazuhiro, Jinno, Hiromitsu, Kitagawa, Yuko
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317889/
https://ncbi.nlm.nih.gov/pubmed/24698107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12410
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