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An E2F1-HOXB9 Transcriptional Circuit Is Associated with Breast Cancer Progression
Homeobox B9 (HOXB9), a member of the homeobox gene family, is overexpressed in breast cancer and promotes tumor progression and metastasis by stimulating epithelial-to-mesenchymal transition and angiogenesis within the tumor microenvironment. HOXB9 activates the TGFβ-ATM axis, leading to checkpoint...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4138122/ https://ncbi.nlm.nih.gov/pubmed/25136922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105285 |
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