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Loss of B-cell translocation gene 2 expression in estrogen receptor-positive breast cancer predicts tamoxifen resistance

B-cell translocation gene 2 (BTG2), a gene suppressed in a subset of aggressive breast cancer, is repressed by estrogen. BTG2 inhibits the expression of HER ligands and promotes AKT activation, which plays an essential role in the tamoxifen resistance of estrogen receptor (ER)-positive breast cancer...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cancer Sci
मुख्य लेखकों: Takahashi, Maiko, Hayashida, Tetsu, Okazaki, Hiroshi, Miyao, Kazuhiro, Jinno, Hiromitsu, Kitagawa, Yuko
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: BlackWell Publishing Ltd 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317889/
https://ncbi.nlm.nih.gov/pubmed/24698107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12410
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