Llwytho...

Loss of B-cell translocation gene 2 expression in estrogen receptor-positive breast cancer predicts tamoxifen resistance

B-cell translocation gene 2 (BTG2), a gene suppressed in a subset of aggressive breast cancer, is repressed by estrogen. BTG2 inhibits the expression of HER ligands and promotes AKT activation, which plays an essential role in the tamoxifen resistance of estrogen receptor (ER)-positive breast cancer...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cancer Sci
Prif Awduron: Takahashi, Maiko, Hayashida, Tetsu, Okazaki, Hiroshi, Miyao, Kazuhiro, Jinno, Hiromitsu, Kitagawa, Yuko
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BlackWell Publishing Ltd 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317889/
https://ncbi.nlm.nih.gov/pubmed/24698107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12410
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