High antitumor activity of pladienolide B and its derivative in gastric cancer

The antitumor activity of pladienolide B, a novel splicing inhibitor, against gastric cancer is totally unknown and no predictive biomarker of pladienolide B efficacy has been reported. We investigated the antitumor activity of pladienolide B and its derivative on gastric cancer cell lines and prima...

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Veröffentlicht in:Cancer Sci
Hauptverfasser: Sato, Momoko, Muguruma, Naoki, Nakagawa, Tadahiko, Okamoto, Koichi, Kimura, Tetsuo, Kitamura, Shinji, Yano, Hiromi, Sannomiya, Katsutaka, Goji, Takahiro, Miyamoto, Hiroshi, Okahisa, Toshiya, Mikasa, Hiroaki, Wada, Satoshi, Iwata, Masao, Takayama, Tetsuji
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2014
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317874/
https://ncbi.nlm.nih.gov/pubmed/24635824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12317
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