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Interleukin-6 induces malignant transformation of rat mesenchymal stem cells in association with enhanced signaling of signal transducer and activator of transcription 3

Mesenchymal stem cells (MSCs) have the potential to be the source for cell-based therapies. However, MSCs can undergo malignant transformation in a tumor microenvironment where a high level of interleukin (IL)-6 is present. In this study, we investigated the role of IL-6 and signal transducer and ac...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Cui, Xiangrong, Liu, Jianping, Bai, Lu, Tian, Jie, Zhu, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317870/
https://ncbi.nlm.nih.gov/pubmed/24168060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12313
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