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Apurinic/apyrimidinic endonuclease 1 induced upregulation of fibroblast growth factor 2 and its receptor 3 induces angiogenesis in human osteosarcoma cells

Tumor angiogenesis contributes to inferior prognosis in osteosarcoma. Apurinic/apyrimidinic endonuclease 1 (APE1) and fibroblast growth factor 2 (FGF2) and its receptor 3 (FGFR3) signaling pathway plays an important role in the angiogenic process. In this study we observed that high expression of AP...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Ren, Tao, Qing, Yi, Dai, Nan, Li, Mengxia, Qian, Chengyuan, Yang, Yuxin, Cheng, Yi, Li, Zheng, Zhang, Shiheng, Zhong, Zhaoyang, Wang, Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317824/
https://ncbi.nlm.nih.gov/pubmed/24329908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12334
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