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Nitrogen Starvation and TorC1 Inhibition Differentially Affect Nuclear Localization of the Gln3 and Gat1 Transcription Factors Through the Rare Glutamine tRNA(CUG) in Saccharomyces cerevisiae

A leucine, leucyl-tRNA synthetase–dependent pathway activates TorC1 kinase and its downstream stimulation of protein synthesis, a major nitrogen consumer. We previously demonstrated, however, that control of Gln3, a transcription activator of catabolic genes whose products generate the nitrogenous p...

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Detalhes bibliográficos
Publicado no:Genetics
Main Authors: Tate, Jennifer J., Rai, Rajendra, Cooper, Terrance G.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317654/
https://ncbi.nlm.nih.gov/pubmed/25527290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.173831
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