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Low-molecular-weight peptide inhibits RNA synthesis in human leukemic and phytohemagglutinin-stimulated leukocytes and globin mRNA transcription in differentiating Friend cells.

The RNA synthesis of human leukemic leukocytes and phytohemagglutinin-stimulated lymphocytes is markedly reduced by administration of a low-molecular-weight nonhistone peptide factor from calf thymus. Treatment with the factor strongly inhibits hemoglobin production and globin mRNA transcription in...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Amici, D, Rossi, G B, Cioé, L, Matarese, G P, Dolei, A, Guglielmi, L, Gianfranceschi, G L
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431764/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/269438/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.9.3869
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