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The Conundrum of the High-Affinity NGF Binding Site Formation Unveiled?
The homodimer NGF (nerve growth factor) exerts its neuronal activity upon binding to either or both distinct transmembrane receptors TrkA and p75(NTR). Functionally relevant interactions between NGF and these receptors have been proposed, on the basis of binding and signaling experiments. Namely, a...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4317559/ https://ncbi.nlm.nih.gov/pubmed/25650935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.11.3485 |
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