Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5

Augmented AMP-activated protein kinase (AMPK) activity inhibits cell migration, possibly contributing to the clinical benefits of chemical AMPK activators in preventing atherosclerosis, vascular remodelling and cancer metastasis. However, the underlying mechanisms remain largely unknown. Here we ide...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Yan, Yi, Tsukamoto, Osamu, Nakano, Atsushi, Kato, Hisakazu, Kioka, Hidetaka, Ito, Noriaki, Higo, Shuichiro, Yamazaki, Satoru, Shintani, Yasunori, Matsuoka, Ken, Liao, Yulin, Asanuma, Hiroshi, Asakura, Masanori, Takafuji, Kazuaki, Minamino, Tetsuo, Asano, Yoshihiro, Kitakaze, Masafumi, Takashima, Seiji
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Pub. Group 2015
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317497/
https://ncbi.nlm.nih.gov/pubmed/25635515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7137
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