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Angiogenin promotes tumoral growth and angiogenesis by regulating matrix metallopeptidase-2 expression via the ERK1/2 pathway

Tumor angiogenesis is essential for tumor growth and metastasis and is dependent on key angiogenic factors. Angiogenin (ANG), a 14.2-kDa polypeptide member of the RNase A superfamily, is an angiogenic protein that has been reported to be upregulated and associated with poor prognosis in some human c...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Miyake, M., Goodison, S., Lawton, A., Gomes-Giacoia, E., Rosser, CJ.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317372/
https://ncbi.nlm.nih.gov/pubmed/24561529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2014.2
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