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Controlling complexity and water penetration in functional de novo protein design

Natural proteins are complex, and the engineering elements that support function and catalysis are obscure. Simplified synthetic protein scaffolds offer a means to avoid such complexity, learn the underlying principles behind the assembly of function and render the modular assembly of enzymatic func...

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Detalles Bibliográficos
Publicado en:Biochem Soc Trans
Main Authors: Anderson, J.L. Ross, Koder, Ronald L., Moser, Christopher C., Dutton, P. Leslie
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317335/
https://ncbi.nlm.nih.gov/pubmed/19021506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST0361106
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