Ligand-promoted weakening of intersubunit bonding domains in aspartate transcarbamoylase
The cooperativity and feedback inhibition exhibited by the regulatory enzyme, aspartate transcarbamoylase (carbamoylphosphate: L-aspartate carbamoyltransferase; EC 2.1.3.2), from Escherichia coli are generally attributed to ligand-promoted conformational changes involving alterations in the subunit...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1977
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431727/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/333446/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.9.3777 |
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