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Muscarinic M(1) receptor and cannabinoid CB(1) receptor do not modulate paraoxon-induced seizures

One of the major signs of severe organophosphate poisoning is seizures. Previous studies have shown that both muscarinic agonist- and organophosphate-induced seizures require activation of muscarinic acetylcholine receptors in the central nervous system. Seizures induced by the muscarinic agonist pi...

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Detalhes bibliográficos
Publicado no:Pharmacol Res Perspect
Main Authors: Kow, Rebecca L, Cheng, Eugene M, Jiang, Kelly, Le, Joshua H, Stella, Nephi, Nathanson, Neil M
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4317231/
https://ncbi.nlm.nih.gov/pubmed/25692018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.100
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