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Regulation of proline oxidase activity by lactate.

We found that proline oxidase, the first enzyme of the proline degradative pathway, is inhibited by lactate. The Km of the enzyme for proline increases with increasing concentrations of lactate. Since proline can be a source for gluconeogenesis, regulation of proline degradation by lactate may serve...

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Detalhes bibliográficos
Main Authors: Kowaloff, E M, Phang, J M, Granger, A S, Downing, S J
Formato: Artigo
Idioma:Inglês
Publicado em: 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC431723/
https://ncbi.nlm.nih.gov/pubmed/271958
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