Resolution of prostaglandin endoperoxide synthase and thromboxane synthase of human platelets.
Thromboxane synthase was localized to the microsomes of human platelets. The enzyme was insensitive to sulfhydryl reagents and thiols but was inhibited by 12L-hydroperoxy-5, 8, 10, 14-eicosatetraenoic acid (concentration for 50% inhibition = 0.1 mM). Treatment of microsomes with Triton X-100 solubil...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1977
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431690/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/410024/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.9.3691 |
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