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Poliovirus-specific primer-dependent RNA polymerase able to copy poly(A).

A template-dependent RNA polymerase has been isolated from poliovirus-infected cells by assaying for the ability of the enzyme to copy poly(A) complexed to an oligo(U) primer. The polymerase was solubilized with detergent, and RNA was removed by precipitation with 2 M LiCl. The solubilized polymeras...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Flanegan, J B, Baltimore, D
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1977
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431685/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/198796/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.9.3677
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