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Production of a functional eukaryotic enzyme in Escherichia coli: cloning and expression of the yeast structural gene for imidazole-glycerolphosphate dehydratase (his3).

A cloned segment of yeast DNA containing the structural gene for imidazoleglycerolphosphate dehydratase (D-erythro-imidazoleglycerolphosphate hydro-lase, EC 4.2.1.19) is transcribed and translated in Escherichia coli with sufficient fidelity to produce functional enzyme. This segment of yeast DNA wa...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Struhl, K, Davis, R W
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 1977
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431671/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/341150/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.12.5255
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