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Polioviruses containing picornavirus type 1 and/or type 2 internal ribosomal entry site elements: genetic hybrids and the expression of a foreign gene.

A picornavirus hybrid genome was constructed in which the internal ribosomal entry site (IRES) of encephalomyocarditis virus was inserted between the 5' non-translated region and the open reading frame of poliovirus (PV), type 1 (Mahoney). Upon transfection into HeLa cells, the hybrid RNA replicated...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Alexander, L, Lu, H H, Wimmer, E
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 1994
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43167/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7509072/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.4.1406
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