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Within-Host Nucleotide Diversity of Virus Populations: Insights from Next-Generation Sequencing

Next-generation sequencing (NGS) technology offers new opportunities for understanding the evolution and dynamics of viral populations within individual hosts over the course of infection. We review simple methods for estimating synonymous and nonsynonymous nucleotide diversity in viral genes from N...

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Detalles Bibliográficos
Publicado en:Infect Genet Evol
Main Authors: Nelson, Chase W., Hughes, Austin L.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4316684/
https://ncbi.nlm.nih.gov/pubmed/25481279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.meegid.2014.11.026
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