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Atherosclerotic plaque uptake of a novel integrin tracer (18)F-Flotegatide in a mouse model of atherosclerosis

Rupture of unstable atherosclerotic plaque is the primary event leading to stroke and myocardial infarction. Plaque vulnerability may be induced by macrophage infiltration, neovessel formation and intraplaque instability. A tracer that selectively binds to macrophages and neovascular endothelium may...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Nucl Cardiol
Hauptverfasser: Su, Helen, Gorodny, Natalia, Gomez, Luis Felipe, Gangadharmath, Umesh B., Mu, Fanrong, Chen, Gang, Walsh, Joseph C., Szardenings, Katrin, Berman, Daniel S, Kolb, Hartmuth C., Tamarappoo, Balaji K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4316660/
https://ncbi.nlm.nih.gov/pubmed/24627345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12350-014-9879-3
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