Scutellarin regulates the Notch pathway and affects the migration and morphological transformation of activated microglia in experimentally induced cerebral ischemia in rats and in activated BV-2 microglia

BACKGROUND: Activated microglial cells release an excess of inflammatory mediators after an ischemic stroke. We reported previously that scutellarin effectively suppressed the inflammatory response induced by activated microglia in rats subjected to middle cerebral artery occlusion (MCAO); however,...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Yuan, Yun, Rangarajan, Parakalan, Kan, Enci Mary, Wu, Yajun, Wu, Chunyun, Ling, Eng-Ang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4316603/
https://ncbi.nlm.nih.gov/pubmed/25600517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-014-0226-z
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