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Immune response to immunodominant Mycobacterium tuberculosis antigen ESAT-6 derived peptide is HLA-haplotype dependent

The antigenic proteins of Mycobacterium tuberculosis (Mtb) have been defined. We used synthetic peptides of secreted antigens, early secreted antigenic target 6 (ESAT-6) and cultural filtrate protein-10 (CFP-10), of Mtb and characterized the immune response in context of HLA genes. Humanized mice la...

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Publicat a:Jacobs J Allergy Immunol
Autors principals: Smart, Michele, Behrens, Marshall, David, Luckey, Conway, Catherine, Taneja, Veena
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4316384/
https://ncbi.nlm.nih.gov/pubmed/25664343
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