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Hybridization properties of immunoglobulin mRNA: Failure to detect covalently associated IgG mRNA transcripts of reiterated and unique mouse DNA

Messenger RNAs for antibody heavy (γ) and light (κ) chains were isolated from the polysomes of an IgG-producing mouse myeloma cell line. Polysomes engaged in heavy or light chain synthesis were separated by immunoprecipitation using rabbit antibodies specific for the mouse IgG formed. The mRNAs obta...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Legler, Mary K., Cohen, Edward P.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431624/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/269411/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.8.3528
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