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Oocyte spindle proteomics analysis leading to rescue of chromosome congression defects in cloned embryos

Embryos produced by somatic cell nuclear transfer (SCNT) display low term developmental potential. This is associated with deficiencies in spindle composition prior to activation and at early mitotic divisions, including failure to assemble certain proteins on the spindle. The protein-deficient spin...

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Detalles Bibliográficos
Publicado en:J Proteome Res
Main Authors: Han, Zhiming, Liang, Cheng-Guang, Cheng, Yong, Duan, Xunbao, Zhong, Zhisheng, Potireddy, Santhi, Moncada, Camilo, Merali, Salim, Latham, Keith E.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4316211/
https://ncbi.nlm.nih.gov/pubmed/20883044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr100827j
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