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Stratified control of IGF-I expression by hypoxia and stress hormones in osteoblasts
Bone cells respond to the integrated effects of local and systemic regulation. Here we show that hypoxia and the stress hormones PGE(2) and glucocorticoid interact in complex ways in osteoblasts, converging on insulin like growth factor I (IGF-I) expression. Whereas hypoxia alone rapidly increased t...
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| Published in: | Gene |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4316208/ https://ncbi.nlm.nih.gov/pubmed/24440782 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2014.01.011 |
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