Transfer of codominant markers by isolated metaphase chromosomes in Chinese hamster ovary cells.
Codominant mutations to methotrexate and ouabain resistance in Chinese hamster ovary cells can be transferred to recipient Chinese hamster ovary cells by isolated metaphase chromosomes. For methotrexate, both the structural change and the increased activity of dihydrofolate reductase (5,6,7,8-tetrah...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1977
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC431614/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/269408/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.74.8.3480 |
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